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. 2013 Mar 10;163(3):326–334. doi: 10.1016/j.ijcard.2011.08.849

Table 2.

Modulation of mRNA genes in the intact heart following in vivo I/R. Details of the Affymetyrix microarray analysis is described in the Materials and methods section.

AffyID Symbol Gene title FC P value
Cell migration
1387316_at Cxcl1 Chemokine (C-X-C motif) ligand 1 (KC) 5.00 4.6E−03
1368760_at Cxcl2 Chemokine (C-X-C motif) ligand 2 (MIP2a) 27.68 2.5E−03
1370634_x_at Cxcl3 Chemokine (C-X-C motif) ligand 2 (MIP2b) 4.14 5.2E−03
1367973_at Ccl2 Chemokine (C-C motif) ligand 2 (MCP-1) 5.08 2.4E−04
1370083_at Ccr1 Chemokine (C-C motif) receptor 1 7.21 1.7E−03
1387202_at Icam1 Intercellular adhesion molecule 1 4.30 1.3E−02



Inflammatory mediators
1398256_at Il1b Interleukin 1 beta 12.83 1.4E−03
1387667_at Nos2 Nitric oxide synthase 2, inducible 11.79 1.3E−02
1369191_at Il6 Interleukin 6 9.39 2.9E−03
1387011_at Lcn2 Lipocalin 2 3.95 2.5E−02
1368527_at Ptgs2 Prostaglandin-endoperoxide synthase 2 (Cox-2) 2.70 1.5E−02
1368494_at S100a8 S100 calcium binding protein A8 8.51 2.7E−03
1387125_at S100a9 S100 calcium binding protein A9 8.00 1.8E−04



Tissue remodelling
1398275_at Mmp9 Matrix metallopeptidase 9 10.22 3.2E−03
1367712_at Timp1 TIMP metallopeptidase inhibitor 1 6.36 2.2E−04



Other
1388596_at Cotl1 Coactosin-like 1 3.24 4.5E−03
1373554_at Spsb1 splA and SOCS box containing 1 3.10 6.9E−04