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Histopathologic features of three patient tumors and corresponding tumorgrafts. UW-SCC6 (A), UW-SCC14N (B), and UW-SCC22 (C). Shown are photomicrografts of primary tumor H&E and p16 IHC top two rows in addition to tumorgraft passage 1 H&E, p16 IHC, Trichrome, Rb, and p53. Overall a strong correlation between Rb and p53 staining was observed (Spearman correlation p=0.04). Images at 200×.
