Fig. 5.

Regulation of human and mouse immune system differentiation is largely conserved. (A) Conserved lineage-specific expression of regulators. Shown are mean-centered expression values (red/blue color bar on the right) of regulators with maximal expression in the same lineage in (Left) human and (Right) mouse. Genes are sorted by mouse lineage with maximal expression. Selected gene names are highlighted on the left. (B) Divergent expression of regulators. Shown are mean-centered expression values of selected regulators with coherent expression patterns within each species that differ between the two species (Left, human; Right, mouse). Genes are sorted by mouse lineage with maximal expression. Genes mentioned in the text are marked with bold and asterisks.