TABLE 1.
Comparison of Dry Eye Subgroups
| MGD | Non-SS ATD | SS ATD | |
|---|---|---|---|
| Number (n) | 6 | 4 | 8 |
| Mean age ± SD (yrs) | 43.4 ± 10.6 | 65.7 ± 10.2 | 60.3 ± 7.7 |
| TBUT (s) | 4.1 ± 0.8 | 3.9 ± 2.2 | 2.6 ± 0.9 |
| Schirmer 1 score (mm) | 30.2 ± 8.5 | 8.1 ± 1.9 | 8.3 ± 7.3 |
| Corneal FL staining score | 3 ± 2.7 | 3.5 ± 3.1 | 6.5 ± 5.7 |
| Cong LG score | 0.3 ± 0.4 | 0.5 ± 0.6 | 4.9 ± 2.1 |
| Conjunctivochalasis† | 0.3 ± 0.5 | 0.3 ± 0.5 | 0 |
| Severity level‡ | 1.5 ± 0.5 | 1.5 ± 0.6 | 2.6 ± 0.9 |
| TGF-β activity (pg/mL) | 4821.6 ± 3917.2 | 7938.9 ± 12217.6 | 14413.8 ± 12014.3 (P < 0.05)* |
*
Versus normal control group.
†
0, not present; >0, present.
‡
based on criteria proposed by the DE Workshop.20
FL, fluorescein; LG, lissamine green; TBUT, tear breakup time in seconds.