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Transcription factor-induced T cell subset formation and cytokine production. Transcription factors push CD4+ and CD8+ T cells toward distinct functional phenotypes, thereby influencing the cytokine milieu and direction of the immune response. Th = helper T cell, Tc = cytotoxic T cell, Treg = regulatory T cell, Tfh = T follicular helper cell, TE = effector T cell, IL = interleukin, IFN = interferon.
