Figure 1. Radioligand binding profile of novel psychoactive compounds.
Shown is a three dimensional plot of mean pKi values of the 14 novel psychoactive compounds screened against 49 distinct molecular targets (see Supplementary Tables for mean +/− SEM data). Abbreviations are as in Table 1 except: BZP rat brain site=rat brain benzodiazepine receptor; PBR=peripheral benzodiazepine receptor. See Supplementary Table 6 for pIC50 values