Figure 2. Potent 5-HT2B agonist activity of 5- and 6-APB.
Shown are concentration-response curves for 5- and 6-APB as well as 5-HT (control) –induced mobilization of intracellular Ca++ release at human cloned 5-HT2B receptor expressed in HEK-T cells. Data represent mean +/− S.E.M of triplicate determinations; where no error bar is shown the error was smaller than the bar. The data in the table represent computer-derived estimates from N of at least 3 separate experiments +/− S.E.M.