Figure 1.
This figure shows slow-wave energy and slow-wave activity during chronic partial sleep deprivation for the PER3 genotypes. Mean (± SEM) hourly slow-wave energy (SWE) and slow-wave activity (SWA) as a percentage of baseline at the same corresponding hour derived from the C3 (A, B), Fz (C, D) or O2 (E, F) channels at partial sleep deprivation/restriction night 1 (SR1) and partial sleep deprivation/restriction night 5 (SR5) for hour 1 (H1) and hour 2 (H2) in PER34/4 (open circles), PER34/5 (gray triangles) and PER35/5 (closed circles) subjects. SWE derived from C3 (but not from Fz or O2) was significantly higher during chronic partial sleep deprivation in PER35/5 compared with PER34/4 and PER34/5 subjects. From Goel N, Banks S, Mignot E, et al. PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. PLoS ONE 2009;4:e5874, with permission.