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. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: Bioorg Med Chem. 2012 Aug 28;20(20):6063–6072. doi: 10.1016/j.bmc.2012.08.023

Table 2.

Antibacterial spectrum of activity (µg/ml)

Compd S.
aureus
S.
pyogenes
S.
pneumonia
E.
faecalis
B.
subtilis
B.
anthracis
E. coli
K12
E. coli
ΔtolC
1 12.5 100 200 >200 50 >200 >200 50
6 6.25 25 50 >200 12.5 12.5 >200 6.25
7 12.5 25 200 200 50 25 >200 6.25
8 25 200 200 200 200 12.5 >200 6.25
11 12.5 >200 12.5 100 12.5 12.5 >200 12.5
12 6.25 50 50 100 6.25 12.5 100 6.25
15 6.25 50 50 100 6.25 12.5 50 12.5
16 12.5 50 50 100 25 25 50 6.25
17 6.25 50 50 100 25 25, 200 25
18 6.25 100 200 >200 6.25 25 25 6.25
19 12.5 1005 50 >200 12.5 25 25 12.5
20 6.25 100 200 200 12.5 25 >200 12.5

Organisms abbreviated above are as follows:

S. aureus ATCC 29213; Strep. pyogenes ATCC 700294;Strep. pneumoniae DAW27; E. faecalis ATCC3186; B. subtilis ATCC 23857; B. anthracis Sterne 34F2; E. coli K12; E. coli K12 ΔtolC