Table 2.

Enzymes from E. histolytica related species that degrade host proteins and their implication in virulence.

Parasite	Tissue or protein	Name	Mr (kDa)	Catalytic type	Comment	Reference
E. moshkovskii
	ECM components	—	≈45	CP	Zymogram and activity of proteases secreted in azocasein	[32]
FIC strain	Gelatin	—	90	CP	Zymogram	[33]
Laredo strain	Gelatin	—	90	CP	Zymogram	[33]
E. dispar
	ECM components	EdCP3	≈30	CP	Sequence homology with E. histolytica. Located in cytoplasmic granules	[34, 35]
E. invadens
PZ strain	Gelatin		99, 90	CP	Zymogram	[33]
IP101 strain	Gelatin		99, 90, 45	CP	Zymogram	[33]
IP-1 strain	Gelatin		56, 58–66, 44–54, 43	CP	Zymogram	[36]
	Gelatin		45	SP	Zymogram	[37]
	Gelatin		130–230, 55, 35	CP, MP	Zymogram	[38]
	Gelatin		130–230,  60	CP, MP	Zymogram	[39]
	Azocasein		28	CP	Zymogram	[40]