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(A) Sampling of blood in individuals with mild AP and SAP after the onset of symptoms. (B and C) Serum IL-6 and sIL-6R levels in control patients and patients with mild AP and SAP. (D) IL-6/sIL-6R ratio. (E) Serum IL-8 levels in control patients and patients with mild AP and SAP. (F) Central role of IL-6 trans-signaling during SAP-associated ALI. Results represent mean ± SD (n > 6). *P < 0.05, **P < 0.005, ***P < 0.001.
