Figure 4. CCR2⁺ TILs.

A group of B6 WT mice (n = 10) was inoculated with 1 × 10⁶ SM1WT1 cells. At day 21, tumors were excised and FACS analyses were performed on TILs. Frequencies of CCR2⁺ cells in (A) CD11b⁺ cells, (B) NK cells, (C) CD8⁺ T cells, and (D) CD4⁺Foxp3⁺ Tregs (top 2 right-most images) and CD4⁺Foxp3^– T cells (bottom 2 images) from TILs are shown. The data shown for CCR2⁺ cells are FACS plots concatenated from 10 individual mice.