Table 5.

Outcome data: Hospitalizations and intradialysis symptoms

	Hemodialysis Group (n=450) (867.3 Patient-Years at Risk)		OL-HDF Group (n=456) (863.1 Patient-Years at Risk)		Rate Ratio (95% CI)	Pa
	No. of Events	No. of Events/100 Patient-Years	No. of Events	No. of Events/100 Patient-Years
All-cause hospitalizations	412	47.5	317	36.7	0.78 (0.67–0.90)	0.001
Infections	73	8.4	72	8.3
Vascular access	98	11.3	56	6.5
Heart failure	28	3.2	15	1.7
Ischemic heart disease	25	2.9	16	1.9
Respiratory disease	26	3.0	28	3.2
Gastrointestinal bleeding	10	1.2	4	0.5
Other reasons	152	17.5	126	14.6
Symptomatic hypotension episodesb	8133	937.7	5862	679.2	0.72 (0.68–0.77)	<0.001
Dysrythmiab	444	51.2	477	55.3	1.08 (0.86–1.35)	0.50
Thoracic painb	327	37.7	318	36.8	0.98 (0.75–1.28)	0.87

Data are the number of hospitalizations (hospital admissions per 100 patient-years) and number of complicated dialysis sessions (number of symptoms per 100 patient-years).

^aPenalized quasi-likelihood under restricted maximum likelihood models.

^bPooled data (data were collected 1 month per each 3-month period).