Table 1.
Enrichment of the NCI pathway insulin-mediated glucose transport in the top 250 genes before and after applying PR to the expression profiles of seven brain disorders
| Disease | Before PR | After PR | ||
|---|---|---|---|---|
| Alzheimer’s disease | 0.0000 | (3290) | 0.8839 | (2) |
| Bipolar disorder | 0.0000 | (1763) | 0.0030 | (431) |
| Glioblastoma | 0.0000 | (1963) | 0.8340 | (4) |
| Huntington’s disease | 0.0060 | (130) | 0.3804 | (22) |
| Rett syndrome | 0.0000 | (3244) | 0.6333 | (9) |
| Schizophrenia | 0.0000 | (3115) | 0.0000 | (3459) |
| Senescence | 0.0000 | (3384) | 0.0067 | (265) |
The values are the posterior probabilities reported by MGSA, where higher value indicates a higher probability that the pathway is enriched. In parentheses, we report the rank of the pathway among 5273 gene sets.