Table 1. Effect of Chitosan Concentration on TMP-Loaded Chitosan/Alginate Nanoparticle Formulationsa.
chitosan concentration (mg/mL) | particle size (nm) | PI | zeta potential (mV) | loading (μg/mg formulationb) |
---|---|---|---|---|
0.5 | 434 ± 39 | 0.31 ± 0.21 | –32 ± 2 | 2.4 ± 0.3 |
1.5 | 563 ± 93 | 0.45 ± 0.15 | –37 ± 6 | 9.1 ± 0.2 |
3 | 970 ± 65 | 0.71 ± 0.13 | –31 ± 7 | 18.8 ± 1.2 |
Results are expressed as mean ± standard deviation (SD; n = 3).
Formulation weight includes the total of chitosan and alginate weight.