Table 2. Conjugation of Humanized Anti-DR5 Antibody to the Surface of Chitosan/Alginate Nanoparticlesa.
| formulation | particle size (nm) | PI | zeta potential (mV) | conjugation efficiency (μg/mg formulationb) |
|---|---|---|---|---|
| conjugation in presence of EDC | 512 ± 42 | 0.28 ± 0.12 | –31 ± 7 | 6.3 ± 1.5c |
| conjugation in absence of EDC | 486 ± 78 | 0.38 ± 0.09 | –32 ± 12 | 0.4 ± 0.1 |
a
Results are expressed as mean ± standard deviation (SD; n = 3).
b
Formulation weight includes the total of chitosan and alginate weight.
c
p < 0.05.