Figure 1.

A, Dengue virus titer kinetics in primary monocyte-derived macrophages from 5 donors in the absence (black bars) or presence (gray bars) of dexamethasone as determined by LLC-MK₂ plaque assay. B–K, Equivalent kinetic assessment of cytokines and chemokines was conducted by performing custom Bio-Plex multiplex analysis with a Luminex 200 analyzer. Error bars represent standard errors, with significance (*α < .05, **α < .01) assessed by Mann-Whitney U nonparametric tests, owing to failure of Levene's test for homogeneity. All x-axis values represent days after infection (days 1, 3, and 5). Abbreviations: G-CSF, granulocyte colony-stimulating factor; IFN-γ, interferon γ; IL-6, interleukin 6; IL-8, interleukin 8; IL-10, interleukin 10; IL-17A, interleukin 17A; MCP-1, monocyte chemoattractant protein 1; MIF, macrophage migration inhibitory factor; PFUs, plaque-forming units; TNF- α, tumor necrosis factor α.