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Drug release profiles of pure pyridostigmine in dissolution medium (pH 7.4 PBS), and PPNMCs in four types of dissolution medium (pH 7.4 PBS, 0.1 mol/L HCL, pH 6.8 PBS, and 0.1 mol/L HCl for 2 hours and subsequently pH 6.8 PBS for 70 hours).
Abbreviations: PPNMCs, nanosized pyridostigmine-poly(lactic acid) microcapsules; PBS, phosphate buffer solution; PYR, pyridostigmine.
