Table 4.
Patients with normal baseline creatinine clearance (> 60 ml/min)
| Group 1 (n=15) | Group 2 (n=85) | p–value | |
|---|---|---|---|
| Gender (m/f) |
2/13 |
24/61 |
0.22 |
| Age (yrs.) |
58 (30–65) |
52 (16–69) |
0.39 |
| BMI (kg/m2) |
26.7 (23.2–36.0) |
24.8 (16.0–36.2) |
0.05 |
| Hematocrit before TPL (%) |
31.5 (15.3–40.0) |
35.3 (21.7–49.6) |
0.01 |
| Platelets before TPL (103/μl) |
83 (42–185) |
92 (27–285) |
0.32 |
| MELD (corrected) |
23 (6–31) |
17 (7–33) |
0.014 |
| MELD (uncorrected) |
21 (6–31) |
12 (6–32) |
0.13 |
| CHILD (A/B/C in %) |
23.1/30.8/46.1 |
35.4/41.8/22.8 |
0.20 |
| Diabetes mellitus (%) |
33.3% |
16.8% |
0.12 |
| Admission from (Home/ward/ICU in %) |
66.6/13.3/20.0 |
88.2/4.7/7.1 |
0.09 |
| ASA class (II/III/IV in %) |
6.7/53.3/40.0 |
11.8/61.2/27.0 |
0.55 |
| Operating time (min) |
390 (275–705) |
355 (240–570) |
0.11 |
| Estimated intraoperative Blood loss (ml) |
3000 (500–15000) |
1000 (300–10000) |
0.05 |
| Marginal grafts (%) |
46.7 |
35.3 |
0.40 |
| Transfusion of – RBC (Unit) |
2 (0–47) |
3 (0–23) |
0.36 |
| - FFP (Unit) |
12 (0–77) |
12 (0–50) |
0.62 |
| - Platelets (Units) |
1 (0–12) |
0 (0–18) |
0.37 |
| - Fibrinogen (g) |
2 (0–22) |
0 (0–12) |
0.08 |
| Length of stay in ICU (days) |
8 (3–54) |
4 (2–31) |
0.0003 |
| Readmissions (%) |
33.3 |
16.5 |
0.006 |
| Incidence of Sepsis (%) |
40.0 |
3.5 |
0.0001 |
| Incidence of Respiratory Failure (w. reintubation) (%) |
26.7 |
5.9 |
0.009 |
| Reoperations (%) |
40.0 |
10.6 |
0.001 |
| Bilirubin peak (μmol/l) |
157 (65–475) |
87 (13–453) |
0.003 |
| ALT peak (U/l) |
1625 (346–5147) |
870 (133–7249) |
0.02 |
| AST peak (U/l) | 1926 (389–10740) | 1047 (114–13560) | 0.02 |
Data expressed as median (range) or number of patients (percentage), TPL indicates transplantation, MELD model for end stage liver disease and ICU intensive care unit, respectively.