Figure 5. S100 at NMJs of EOM and limb muscles from ALS SOD1^G93A mice.

Confocal images of NMJs from control (A, C) and SOD1^G93A transgenic mice (B, D) at 159 and 157 days, respectively, double-labeled with α-bungarotoxin (BTx, red) and antibody against S100 (green). Note that S100 immunoreactivity was lacking at nerve terminals and motor end plates from both EOMs and limb muscles of transgenic mice at terminal stages. Bar = 24 µm.