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. 2012 Nov 23;13:661. doi: 10.1186/1471-2164-13-661

Table 1.

Brain eQTLs found in predicted miRNA-mRNA binding sites

mirSNP Gene Involved miRNAs Allele eQTL Linkagea p-value (Myers, A.J. et al)b p-value (Colantuoni, C. et al)c p-value (Gibbs, J.R. et al)d
rs3087822
CRIPT
hsa-miR-200a-3p, hsa-miR-26b-3p, hsa-miR-29b-1-5p, hsa-miR-335-3p
A/G
rs3087822
1
8.45E-05
9.54E-18
3.20E-13
rs13042
FAM82B
hsa-miR-202-5p, hsa-miR-362-5p, hsa-miR-500b, hsa-miR-1914-5p
A/Ge
rs13042/rs4961193
1/0.864
5.03E-06
8.52E-16
1.30E-08
rs1058381
RABEP1
hsa-miR-4760-3p
A/G
rs1058381/rs1065483
1/0.954
0.00254
7.81E-19
2.89E-08
rs1058398 RABEP1 hsa-miR-134, hsa-miR-3118, hsa-miR-943, hsa-miR-192-3p, hsa-miR-5002-3p A/G rs1065483 0.955 0.00254 7.81E-19 3.92E-10

aLinkage analysis of predicted miRNA-related SNPs and eQTLs in 90 CEU individuals from HapMap project.

bA survey of gene expression of 193 normal human brain tissues (cortex) [22]. The p-values have been adjusted by Bonferroni correction.

cA survey of gene expression of 269 normal human brain tissues (prefrontal cortex) [23]. Genome-wide Bonferroni corrected p = 0.05 (2.6e-12).

dA survey of gene expression of 150 normal human brain tissues (cerebellum, frontal cortex, pons, and temporal cortex) [24].

eAlthough rs13042 has four allelotypes in MirSNP, only A and G alleles have frequencies in populations.