Table 4.

Experimentally validated miRNA-related SNPs found in MirSNP

MiRNA	Target gene	Functional SNP	Reported associated disease	MirSNP	PolymiRTS2	Mirsnpscore	Patrocles	Pubmed id	Journal	Author
hsa-mir-629	NBS1	rs2735383	Lung cancer					22114071	Carcinogenesis	Yang L
hsa-mir-184	TNFAIP2	rs8126	Squamous cell carcinoma of the head and neck	✓	✓			21934093	Carcinogenesis	Liu Z
hsa-mir-1827	MYCL1	rs3134615	Small-cell lung cancer	✓		✓	✓	21676885	Cancer Res	Xiong F
hsa-mir-148a	HLA-C	rs67384697	HIV	✓				21499264	Nature	Kulkarni S
hsa-mir-191	MDM4	rs4245739	Ovarian carcinomas	✓		✓		21084273	Cancer Res	Wynendaele J
hsa-mir-125b	BMPR1B	rs1434536	Breast cancer	✓	✓	✓	✓	19738052	Cancer Res	Saetrom P
hsa-mir-510	HTR3E	rs56109847	Diarrhea predominant irritable bowel syndrome	✓	✓			18614545a	Hum. Mol. Genet	Kapeller J
hsa-mir-96	HTR1B	rs13212041	Arson or property damage					18283276a	Mol. Psychiatry	Jensen KP
hsa-mir-433	FGF20	rs12720208	Parkinson’s disease	✓		✓		18252210a	Am. J. Hum. Genet	Wang G
hsa-mir-148/152	HLA-G	rs1063320	Childhood asthma	✓	✓	✓	✓	17847008a	Am. J. Hum. Genet	Tan Z
hsa-mir-24	DHFR	rs34764978	Methotrexate resistance					17686970a	PNAS	Mishra PJ
hsa-mir-155	AGTR1	rs5186	Hypertension	✓	✓			17668390a	Am. J. Hum. Genet	Sethupathy P
hsa-mir-206	ESR1	rs9341070	Breast cancer					17312270a	Mol. Endocrinol	Adams BD
hsa-mir-24	SLITRK1	rs193302862	Tourette’s syndrome	✓				16224024a	Science	Abelson JF

Some cases are not in MirSNP because the SNPs were not located in the 3’UTR based on our records (rs34764978, rs13212041) or do not have a perfect 7-nt binding in the seed site (rs2735383, rs9341070).

^aThese cases are from Table 2 in Sethupathy and Collins [34].