Figure 4.

Results of serum GIA for 10 μg and 50 μg MSP1₄₂ (FVO)/AS01 vaccine in malaria-naïve adults. Percent parasite growth inhibition against P. falciparum FVO clone parasites from the US MSP1₄₂ FVO/AS01 study. The net percent growth inhibition of pre-and post third immunization sera obtained for 10 μg and 50 μg MSP1₄₂/AS01 dose subjects is shown tested at 20% (v/v, final). Dashed horizontal lines indicate the median response, while the filled bars indicate the 25 and 75% quartiles. Individual responses are represented as either filled circles for the 10 μg or filled squares for the 50 μg dose subjects. P value calculated from two-tailed t-test.