Table 2.
Solicited adverse events post-vaccination (day 0–7) in the Phase 1 Kenya study
| |
50 μg MSP142/AS01 (N = 20*) |
Rabies comparator (N = 10*) |
||||
|---|---|---|---|---|---|---|
| G1 | G2 | G3 | G1 | G2 | G3 | |
|
Pain | ||||||
| Immunization 1 |
14 |
6 |
0 |
6 |
0 |
0 |
| Immunization 2 |
12 |
7 |
0 |
5 |
0 |
0 |
| Immunization 3 |
10 |
4 |
0 |
4 |
0 |
0 |
|
Redness | ||||||
| Immunization 1 |
1 |
0 |
0 |
0 |
0 |
0 |
| Immunization 2 |
3 |
0 |
0 |
2 |
0 |
0 |
| Immunization 3 |
0 |
0 |
1 |
0 |
0 |
0 |
|
Swelling | ||||||
| Immunization 1 |
6 |
0 |
0 |
2 |
0 |
0 |
| Immunization 2 |
3 |
0 |
0 |
2 |
0 |
0 |
| Immunization 3 |
1 |
0 |
1 |
1 |
0 |
0 |
|
Fever | ||||||
| Immunization 1 |
0 |
0 |
0 |
0 |
0 |
0 |
| Immunization 2 |
1 |
0 |
0 |
0 |
0 |
0 |
| Immunization 3 |
1 |
0 |
0 |
0 |
0 |
0 |
|
Fatigue | ||||||
| Immunization 1 |
2 |
3 |
0 |
1 |
0 |
0 |
| Immunization 2 |
1 |
1 |
0 |
1 |
0 |
0 |
| Immunization 3 |
2 |
0 |
0 |
0 |
0 |
0 |
|
Nausea | ||||||
| Immunization 1 |
3 |
0 |
0 |
1 |
0 |
0 |
| Immunization 2 |
0 |
1 |
0 |
0 |
0 |
0 |
| Immunization 3 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Headache | ||||||
| Immunization 1 |
8 |
4 |
0 |
1 |
0 |
0 |
| Immunization 2 |
3 |
0 |
1 |
0 |
0 |
0 |
| Immunization 3 |
4 |
2 |
0 |
0 |
1 |
0 |
|
Malaise | ||||||
| Immunization 1 |
2 |
1 |
0 |
0 |
0 |
0 |
| Immunization 2 |
2 |
3 |
0 |
0 |
0 |
0 |
| Immunization 3 |
1 |
1 |
0 |
0 |
0 |
0 |
|
Myalgia | ||||||
| Immunization 1 |
1 |
0 |
0 |
1 |
0 |
0 |
| Immunization 2 |
1 |
2 |
0 |
0 |
0 |
0 |
| Immunization 3 |
1 |
0 |
0 |
0 |
0 |
0 |
|
Joint Pain | ||||||
| Immunization 1 |
2 |
1 |
0 |
1 |
0 |
0 |
| Immunization 2 |
1 |
2 |
0 |
0 |
0 |
0 |
| Immunization 3 | 1 | 0 | 0 | 1 | 0 | 0 |