Table 1.

Biological activity of compounds of type I and type II

Structure	Compound	Type	R1	R2	R3	R4	Plt aggregation IC50 ± S.E.M (μM)b
	1		H	C = NOH	nC5H11	H	No inhibition
	2		H	COOH	nC5H11	H	No inhibition
	3	I	OH	OCH3	nC5H11	H	7.5 ± 0.8
	4		OH	OCH3	nC4H9	H	14.2 ± 5.7
	5		OH	OCH3	nC9H19	H	97.6 ± 83.5
	6		OH	OCH3		H	41.2 ± 0.7
	7		OH	OCH3	Ph	H	8.5 ± 1.2
	8	II	OH	OCH3	a	H	13.4 ± 0.5
	9		OH	OCH3	Ph	CH3	11.3 ± 4.8
	10		OCH3	OCH3	Ph	H	No inhibition

a = 4-Fluorophenyl; ^bn = 3–4 in all experiments.