Table 1.
Structural similarity between hCE1 and cholinesterases as demonstrated using DALI. Data are ranked based upon Z score, with only the highest scoring cholinesterase sequences listed.
| Rank | Name | Za | rmsd (Å) | Number of residues | Identity (%) | Description | Species |
|---|---|---|---|---|---|---|---|
| 1 | 1MX5 | 78.7 | 0 | 532 | 100 | Liver CE | Human |
| 73 | 2J4C | 56.7 | 1.9 | 524 | 34 | BChE | Human |
| 74 | 2WIL | 56 | 1.9 | 526 | 34 | BChE | Human |
| 75 | 2Y1K | 56.5 | 1.9 | 525 | 34 | BChE | Human |
| 76 | 2WIG | 56.2 | 1.9 | 526 | 34 | BChE | Human |
| 77 | 1P0P | 56.2 | 1.9 | 522 | 34 | BChE | Human |
| 78 | 2WIF | 56.1 | 1.9 | 527 | 34 | BChE | Human |
| 79 | 2ACK | 56.1 | 2.0 | 527 | 35 | AChE | Torpedo californica |
| 80 | 2ACE | 56.1 | 2.0 | 527 | 35 | AChE | Torpedo californica |
| 213 | 3LII | 53.4 | 2.1 | 534 | 34 | AChE | Human |
| 339 | 1B41 | 46.5 | 2.0 | 531 | 34 | AChE | Human |
| 342 | 1F8U | 46.4 | 2.0 | 531 | 34 | AChE | Human |
| 343 | 2X8B | 46.1 | 2.1 | 537 | 34 | AChE | Human |
a
Z-scores represent number of standard deviations from the mean, and values less than 2 are not considered statistically significant.