Figure 1. VEGF induced cerebrovascular dysplasia in mice with Eng+/− BM.
(A) Representative images of VEGF-induced brain angiogenic foci. Arrows indicate dysplastic vessels. Scale bar: 50μm. Quantifications of (B) vascular density and (C) dysplasia index. *: p<0.001 compared to WT/WT BM group. #: p<0.001 compared to Eng+/−/WT BM group. Data: mean±SD. n=6 per group.