Table 2.
| a: Concentration of Urine Proteins in Different Histological Groups at One-Year Post Transplant [median (25%,75%)] | ||||||
|---|---|---|---|---|---|---|
| Protein/Cr (mg/g) | Albumin/Cr (mg/g) | IgG (mg/g) | IgM (mg/g) | α1m (mg/g) | RBP (µg/g) | |
| All Patients (N= 221) | 84.7 (54.3, 164.0) | 16.2 (4.4, 56.8) | 2.5 (0.1,7.6) | 41.4 (9.3, 119.7) | 17 (9.9, 32.5) | 166.7 (91, 587.6) |
| Normal (N= 84) | 75.5 (52.6, 139.4) | 12.0 (0.1, 34.6) | 0.1 (0.1, 6.5) | 37.2 (0.0, 87.7) | 15.2 (6.8, 29.3) | 127.7 (73.1, 412.6) |
| IFTA (N= 79) | 85.7 (59.7, 189.7) | 19.7 (0.1, 189.7) | 3.1 (0.1, 8.5) | 50.3 (7.3, 152.7) | 19.9 (9.9, 31.8) | 198.3 (101.9, 689.9) |
| Inflammation (N= 14) | 142.9 (70.3, 281.1) | 24.9 (11.8, 101.1) | 5.1 (2.3, 34.6)* | 147.3 (86.3, 474.4)# | 39.2 (14.0, 60.1) | 624.4 (112.1, 2239.6) |
| GN (N= 33) | 100.3 (49.3, 355.1) | 24.9 (6.5, 136.1)# | 3.3 (0.1, 11.5) | 36.1 (17.2, 98.6) | 20.6 (3.5, 36.2) | 242.9 (75.8, 1363.4) |
| Vascular (N= 11) | 73.2 (54.9, 111.7) | 8.1 (6.0, 34.3) | 0.1 (0.1, 4.4) | 50.4 (0.0, 33.9) | 14.9 (10.0, 23.2) | 163.0 (80.5, 315.8) |
| Kruskall Wallis | 0.286 | 0.052 | 0.051 | 0.002 | 0.07 | 0.131 |
| b: Concentration of Urine Proteins for Different Histology Risk Groups at One-Year [median (25%, 75%)] | ||||||
| Protein/Cr (mg/g) | Albumin/Cr (mg/g) | IgG (mg/g) | IgM (mg/g) | α1m (mg/g) | RBP (µg/g) | |
| All Patients (N= 216) | 84.5 (54.3, 161.0) | 16.2 (3.6, 57.1) | 2.4 (0.1, 7.5) | 39.4 (7.8, 106.6) | 16.2 (9.7, 30.8) | 165.9 (90.6, 569.7) |
| Normal (N= 90) | 73.2 (52.5, 131.9) | 12.0 (0.1, 34.3) | 0.1 (0.1, 6.5) | 34.0 (0.0, 75.4) | 14.6 (6.4, 26.1) | 127.2 (76.0, 392.7) |
| IFTA (N= 72) | 87.5 (56.5, 188.2) | 18.1 (0.1, 60.9) | 2.9 (0.1, 7.6) | 36.3 (0.0, 116.9) | 19.6 (9.7, 29.8) | 166.8 (94.1, 662.9) |
| IFTA + i (N= 21) | 100.8 (68.1, 235.3)* | 32.3 (6.4, 73.6)* | 5.3 (0.1, 15.5)# | 106.6 (44.1, 214.0)# | 23.0 (13.7, 46.3)# | 256.3 (156.9 992.3)# |
| GN (N= 33) | 100.3 (49.3, 355.1) | 24.9 (6.5, 136.1)# | 3.3 (0.1, 11.5) | 36.1 (17.2, 98.6) | 20.6 (9.5, 36.2) | 242.9 (75.8, 1363.4) |
| Kruskall Wallis | 0.134 | 0.021 | 0.083 | 0.016 | 0.04 | 0.053 |
#
p < 0.013,
*
p < 0.05 Mann Whitney post Hoc compared to Normal.
#
p < 0.017,
*
p < 0.05 Mann Whitney post Hoc compared to Normal.
IFTA is Interstitial Fibrosis and Tubular Atrophy, GN is Glomerular