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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Immunobiology. 2012 Aug 9;218(4):674–682. doi: 10.1016/j.imbio.2012.08.269

Figure 1. Pre-treatment with rIL-2 leads to the amelioration of EAE.

Figure 1

Figure 1

C57BL/6 mice were immunized with MOG35-55 peptide emulsified in complete Freund’s adjuvant along with 200 ng of pertussis toxin (day 0) and 400 ng pertussis toxin (Day 2). Mice pre-treated with rIL-2 received an i.p. injection with 10,000 U of rIL-2 three times a day for three days and once on day 4 prior to EAE induction (day 0 of immunization). (A) Clinical scores were recorded daily after EAE induction. (B) H&E spinal cord histopathology collected 15 days after immunization.