Table 3.

Effect of SNP rs2070704 on Ischemic Stroke Risk

			Minimally adjusted model†		Full model‡
Subjects	Cases/controls	MAF (G allele) cases/controls	OR (95%CI)	P	OR (95%CI)	P
Entire Population	829/899*	0.203/0.238	0.83 (0.7-0.9)	0.025	0.74(0.6-0.9)	0.001
Stratified
Blacks	355/351	0.225/0.288	0.71 (0.5-0.9)	0.007	0.68 (0.5-0.9)	0.005
Black Female	157/160	0.229/0.259	0.88 (0.6-1.3)	0.490	0.83 (0.6-1.2)	0.311
Black Male	198/191	0.215/0.312	0.58 (0.4-0.8)	0.002	0.55 (0.4-0.8)	0.002
Whites	431/500	0.188/0.205	0.93 (0.7-1.2)	0.499	0.82 (0.6-1.0)	0.107
White Female	165/215	0.210/0.209	1.03 (0.7-1.5)	0.867	0.88 (0.6-1.3)	0.530
White Male	266/285	0.174/0.202	0.85 (0.6-1.2)	0.291	0.80 (0.6-1.0)	0.093

†: Age, Gender, Race.

‡: Age, Gender, HTN, DM, MI, Smoking, Oral Contraceptive use, Race.

* Of the 830 cases and 907 controls, 3 cases and 6 controls failed genotyping at rs2070704.