Table 2.
36-Month Bayley Scales of Infant Development-II Scores and Other Major Neurodevelopmental Outcomes by Treatment
|
Early Intervention and Health Care Counseling |
Resuscitated Health Care Counseling Only (Control) |
MD (95% CI) / RR (95% CI) |
Early Intervention and Health Care Counseling |
Non-resuscitated Health Care Counseling Only (Control) |
MD (95% CI) / RR (95% CI) |
Early Intervention and Health Care Counseling |
Combined Health Care Counseling Only (Control) |
MD (95% CI) / RR (95% CI) |
|
|---|---|---|---|---|---|---|---|---|---|
| 36- month BSID-II evaluation complete - N | 59 | 64 | 87 | 83 | 146 | 147 | |||
| MDI-mean±SD | 102.6 ±9.8 | 98.0 ±14.6 | 4.63 (0.93,oo) | 100.1 ±10.7 | 97.7 ±10.4 | 2.41 (−0.79, 5.62) | 101.1 ±10.4 | 97.8 ±12.4 | 3.30(0.67,5.93) |
| PDI-mean±SD | 108.7 ±12.0 | 103.3 ±17.0 | 5.41 (0.17, 10.65) | 105.4±15.3 | 99.3 ±17.4 | 6.08(1.13, 11.03) | 106.7 ±14.1 | 101.0 ±17.3 | 5.69(2.06,9.31) |
| MD<85-n/N(%) | 2/59 ( 3.4) | 7/64 (10.9) | 0.31(0.07, 1.43) | 3/87 ( 3.4) | 8/83 ( 9.6) | 0.36(0.10, 1.30) | 5/146 ( 3.4) | 15/147(10.2) | 0.34(0.13,0.90) |
| MDI<70-n/N(%) | 1/59 ( 1.7) | 4/64 ( 6.3) | 0.27 (0.03, 2.36) | 2/87 ( 2.3) | 0/83 ( 0.0) | - | 3/146 ( 2.1) | 4/147 ( 2.7) | 0.76(0.17,3.32) |
| PDI <85 - n/N (%) | 3/59 ( 5.1) | 7/64 (10.9) | 0.46(0.13, 1.72) | 5/87 ( 5.7) | 12/83 (14.5) | 0.40(0.15, 1.08) | 8/146 ( 5.5) | 19/147 (12.9) | 0.42(0.19,0.94) |
| PDI <70 - n/N (%) | 1/59 ( 1.7) | 3/64 ( 4.7) | 0.36(0.04,3.38) | 4/87 ( 4.6) | 7/83 ( 8.4) | 0.55(0.17, 1.79) | 5/146 ( 3.4) | 10/147 ( 6.8) | 0.50(0.18, 1.44) |
One-sided t-test and mean difference confidence interval were applied to test the primary hypothesis that the intervention group will improve the Bayley Scales of Infant Development 2ntl Edition (BSID-II) Mental Development Index (MDI) at 36 months compared to the control group among resuscitated infants. Two-sided t-tests and mean difference confidence intervals were applied to the BSID-II MDI scores among the non-resuscitated infants and the BSID-II Psychomotor Development Index (PDI) scores among the resuscitated and non-resuscitated infants.