Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Biol Inorg Chem. 2013 Jan 19;18(3):289–297. doi: 10.1007/s00775-012-0973-1

FIG. 2.

FIG. 2

Changes at residue 41 in cyt c modulate caspase activation. Cleavage of the caspase 3 substrate Ac-DEVD-AMC was monitored at 37°C in U937 cytosol with the addition of 10 nM WT, G41S, G41A or G41T, 50 nM G41T, 100 nM G41T cyts c or PBS at pH 7.25. All reactions contained 1 mM dATP and 5 mM DTT. The error bars have been omitted to improve the clarity of the figure. The full figure with error bars is in the Supplementary Material (Figure S1).