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. 2013 Feb 27;5:1. doi: 10.3389/fnsyn.2013.00001

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Copyright © 2013 Johnstone and Raymond.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Enhanced presynaptic function associated with LTP3 is dependent on postsynaptic translation. (A) Scatter plot showing the half-life of FM 1-43 destaining versus distance to filled dendrite for individual terminals in slices stimulated with 8TBS with and without gelonin in the patch pipette. (B) Histogram summarizing destaining rate data obtained from the “Control” group in (A) except with distances binned. There was no effect of distance on mean half-life of destaining in untreated cells. (C) Histogram summarizing data obtained from “gelonin” group in (A) except with distances binned. Inclusion of gelonin in the patch pipette abolished enhanced release induced by 8TBS only at sites close to the treated postsynaptic cell (One-Way ANOVA, ^*p < 0.05).