Figure 2.

Schematic sequence of tissue expander inflation. At biological equilibrium, the skin is in a physiological state of resting tension, left. A tissue expander is implanted subcutaneously between the skin, consisting of the epidermis and dermis, and the hypodermis. When the expander is inflated, the skin is loaded in tension, top. Mechanical stretch induces cell proliferation causing the skin to grow. Growth restores the state of resting tension, right.