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. 2012 Aug 29;7:146. doi: 10.1186/1748-717X-7-146

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Copyright ©2012 Barth et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A. Kaplan-Meier estimates of overall survival for all newly diagnosed glioblastoma (WHO grade 4, n = 21). The median survival time of boron neutron capture therapy (BNCT) group (blue line) is 15.6 months. There is statistical significance between both group Log-rank test (p = 0.0035). B. Kaplan-Meier estimates of overall survival for all newly diagnosed glioblastoma (protocol 1 and 2). External beam X-ray irradiation (XRT) boost after boron neutron capture therapy (BNCT) was carried for the latter 11 cases. This improved the median survival time to 23.5 months (from 14.1 months for BNCT only, protocol 1, dotted line in blue).