Appendix FIG. A1.

Analysis of the inflammatory response induced by hydrogel in rat. Two weeks after of intramuscular or subcutaneous hydrogel (hyaluronic acid:gelin [40:60], extralinker ratio 1:8) injections, the inflammatory response was examined by immunochemistry. The injection of saline was used as control. The tissues were labeled with antibody against CD68 (anti-inflammatory macrophages) and reveled with Vector DAB (brown). Hematoxylin–eosin counterstained (blue). Optical microscopy images with magnification (× 10). Color images available online at www.liebertpub.com/tec