Table 2.
Genotype distribution and frequency of the 5HTTLPR and 5HT1B G861C polymorphism
| Group | n |
5HTTLPR genotype frequency (%) |
χ² | P-value |
5HT1B G861C genotype frequency (%) |
χ² | P-value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| S/S, S/LG, LG/LG | S/LA, LG/LA, LA/LA, S/XL, LA/XL, LG/XL | G/G | G/C | C/C | ||||||
| AS-ALC |
120 |
90 (75.0) |
30 (25.0) |
5.39 |
0.02a* |
25 (20.8) |
70 (58.3) |
25 (20.8) |
4.58 |
0.10a |
| AS-N-ALC |
153 |
100 (65.4) |
53 (34.6) |
2.95 |
0.09b |
44 (28.8) |
74 (48.4) |
35 (22.9) |
3.07 |
0.22b |
| Controls | 191 | 119 (62.3) | 72 (37.7) | 5.50 | 0.06c | 55 (28.8) | 88 (46.1) | 48 (25.1) | 5.04 | 0.28c |
AS-ALC: Antisocial alcoholism;
AS-N-ALC: Antisocial personality disorder without alcoholism.
a AS-ALC vs. Healthy Controls.
b AS-ALC vs. AS-N-ALC.
c AS-ALC vs. AS-N-ALC vs. Controls.
*P < 0.05.