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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Hepatology. 2013 Jan 10;57(2):775–784. doi: 10.1002/hep.26065

Figure 3. Total flux signal captured by Luciferin-expressing, transplanted cells in grafts of cells in hyaluronans versus injected as a cell suspension in healthy and CCl4 -induced liver injury models.

Figure 3

Flux readings are normalized to those in control animals receiving no cell transplant. Much higher flux signals are observed in grafted cells, both in the healthy and injured models, most noticeably in the first 12 and 24 hrs post-transplant. By 72 hrs, the signal is lost in all cases due to silencing mechanisms involving methylation of the CMV promoter in the adenoviral vector.