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53BP1 alters the cell cycle in ovarian cancer cell lines. To explore the potential mechanism through which 53BP1 inhibits cell growth, the cell cycle was assayed by flow cytometry. As shown, compared to A2780/pLPC-vector (B, 14.93±0.58%), HO-8910PM/pNG-53BP1 (D, 7.82±0.48%), 35.90±1.30% of A2780/pLPC-53BP1 (A) and 12.52±0.32% of HO-8910PM/pNG-vector cells (C) were in G2/M phase. (E and F) The flow cytometric data. Data are representative of three independent experiments.
