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. Author manuscript; available in PMC: 2013 Feb 27.
Published in final edited form as: J Immunol. 2011 Mar 18;186(9):5236–5243. doi: 10.4049/jimmunol.1001078

FIGURE 5.

FIGURE 5

LeTx-induced activation of macrophage K+ channels does not require caspase-1 activation. A, Overlay of typical current traces recorded from C57BL/6 BMDMs treated with LeTx (LF and PA, 100 ng/ml), as compared with an untreated control cell. Mean peak Kir (B) and Kv (C) current densities recorded at −95 mV and +60 mV, respectively, for the cell populations described above with 5–20 cells per condition in three to five independent experiments and are expressed as the mean ± SEM. The LeTx induction of increased Kir and Kv current densities were significant compared with the untreated control cells. ***p < 0.001.