. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Cancer Causes Control. 2012 Dec 28;24(3):421–426. doi: 10.1007/s10552-012-0127-3

Table 1.

Comparison of clinical characteristics by BRCA mutation status

	BRCA (−) (n=67)	BRCA1 (+)(n=21)	BRCA2 (+)(n=8)	p-value
Age (years)	35.3±4.2	34.1±4.9	32.0±3.4	0.11
Parity ≥1	9.8%	15.0%	25.0%	0.45
BMI (Kg/m²)	22.8±3.4	21.5±1.7	21.2±2.0	0.42
Age at menarche (years)	12.7±1.6	12.7±1.6	12.0±1.9	0.84
Family history of breast/ovarian cancer^*	29.3%	38.1%	75.0%	0.04
History of infertility^†	15.4%	15.0%	0.0%	0.54
Cancer
Stage				0.46
≤II	94.5%	93.3%	80.0%
III	5.5%	6.7%	20.0%
ERα	92.2%	35.3%	100.0%	<0.001
PR	81.4%	25.0%	100.0%	<0.001
Her2/neu	34.0%	14.3%	40.0%	0.33
Triple-negative	3.3%	53.3%	0.0%	<0.001

Abbreviation: ERα, estrogen receptor α; PR, progesterone receptor

History of breast/ovarian cancer in first-degree relatives

^†

Any history of receiving fertility treatment.