Table V.

Part of the differentially expressed genes after ABCE1 inhibition.

Genes	Description	Expression change
MTAP	Nucleotide and nucleic acid metabolism; S-methyl-5-thioadenosine phosphorylase activity	Up-regulated
GADD45	Activation of MAPKKK activity; apoptosis; cell differentiation	Up-regulated
Caspase-7	Apoptosis-related cysteine peptidase	Up-regulated
TANK	Signal transduction; metal ion binding	Up-regulated
ZNF14	Regulation of transcription, DNA-dependent; zinc ion binding	Up-regulated
P27KIP1	Regulation of cyclin dependent protein kinase activity, regulation of cell proliferation	Up-regulated
CIDEB	DNA damage response, signal transduction resulting in induction of apoptosis	Up-regulated
TIMP2	Metalloendopeptidase inhibitor activity	Down-regulated
TNFRSF1B	Cytokine and chemokine mediated signaling pathway, apoptosis	Down-regulated
CDH11	Homophilic cell adhesion; calcium ion binding	Down-regulated
LAMC1	Regulation of epithelial cell proliferation; cell adhesion	Down-regulated
TFF3	Defense response; digestion	Down-regulated
CD55	Complement activation, classical pathway; innate immune response	Down-regulated
CDK4	Cell proliferation; G1/S transition of mitotic cell cycle	Down-regulated