Figure 2.

AdNEP expression inhibits DU145 cell growth. (A) Cells infected with AdNEP or AdLacZ at 10 pfu/cell, or uninfected cells were plated in T25 flask at 1×10⁴ cells per flask in triplicate and total cell numbers were counted at the indicated times. (B) Relative values of the number of cells infected with AdNEP at increasing concentrations compared to cells treated with AdLacZ at 10 pfu/cell. Cell growth was inhibited at 7 days in an adenovirus dose-dependent manner. Values are represented as mean ± SE (n=4). (a, P<0.01 compared with AdLacZ treated cells).