Table 1.
Summary of subject demographics, smoking histories, spirometry and emphysema
| Group | S | COPD | pvalue |
|---|---|---|---|
| Subjects, n |
14 |
20 |
|
| Sex ratio, M/F |
11/3 |
12/8 |
NS |
| Age, years (SD) |
62 (9) |
62 (11) |
NS |
| Smoking, pack-years (SD) |
60 (29) |
62 (41) |
NS |
| Smoking status (Active/Former) |
6/8 |
5/15 |
NS |
| FEV1,% pred (SD) |
91 (16) |
40 (27) |
<0.0001 |
| Emphysema,% (SD) |
12 (14) |
36 (15) |
0.02 |
| Surgical indication (resection/LVRS/transplant) |
14/0/0 |
8/5/7 |
0.001 |
| ICS use (yes/no) |
1/13 |
14/6 |
0.0004 |
| Recent infection (yes/no) | 0/14 | 2/18 | NS |
Data are presented as average (SD), except for sex and smoking status ratios. Former smokers were defined as those subjects that had quit smoking for more than 6 months. Subjects were considered to have a recent infection if they had taken a course of antibiotics in the past 6 weeks. S, smoker without COPD; M, male; F, female; LVRS, lung volume reduction surgery; ICS, inhaled corticosteroids; NS, not significant.