Table 2.
The frequencies of genotypes among DAPK methylated and unmethylated groups
| DAPK unmethylated | DAPK methylated | p value* | |
|---|---|---|---|
| the number of subjects |
231 |
296 |
|
| mean age ± SD |
59.6 ± 13.4 |
62.1 ± 13.8 |
0.035 |
| male : female |
137 : 94 |
182 : 114 |
NS |
|
H. pylori positivity |
122/231 |
216/296 |
<0.0001 |
| non-GC : GC |
211 : 20 |
201 : 95 |
<0.0001 |
| HRH2 rs2607474 genotype |
|
|
|
| GG |
155 |
246 |
<0.0001# |
| GA |
72 |
47 |
|
| AA |
4 |
3 |
|
| A allele frequency | 17.3% | 9.0% | <0.0001 |
*: unmethylated vs. methylated, #: frequency of GG homozygote.
NS: not significant.