Table 6.
Risk of rs2697474 GG homozygote in younger or older subjects
| DAPK methylation | |||||
|---|---|---|---|---|---|
| = < 60 (233) |
GG |
GA |
AA |
GG vs GA + AA; OR (95%CI) |
p value |
| unmethylated (115) |
80 |
32 |
3 |
reference |
- |
| methylated (118) |
96 |
21 |
1 |
2.12 (1.13-3.98) |
0.020 |
| 60 < (294) |
|
|
|
|
|
| unmethylated (116) |
75 |
40 |
1 |
reference |
- |
| methylated (178) |
150 |
26 |
2 |
2.72 (1.55-4.80) |
0.0005 |
| CDH1 methylation |
|
|
|
|
|
| = < 60 (233) |
GG |
GA |
AA |
GG vs A carrier; OR (95%C.I.) |
p value |
| unmethylated (121) |
88 |
29 |
4 |
reference |
- |
| methylated (112) |
88 |
24 |
0 |
1.55 (0.827-2.91) |
0.17 |
| 60 < (294) |
|
|
|
|
|
| unmethylated (160) |
109 |
49 |
2 |
reference |
- |
| methylated (134) | 116 | 17 | 1 | 2.81 (1.53-5.17) | 0.0009 |
by logistic regression analysis after adjustment for age, gender and H. pylori infection status.
(): the number of subjects.