Table 7.
Risk of rs2607474 GG homozygote in H. pylori positive or negative subjects
| DAPK methylation | |||||
|---|---|---|---|---|---|
|
H. pylori negative (189) |
GG |
GA |
AA |
GG vs GA + AA; OR (95%CI) |
p value |
| unmethylated (109) |
73 |
35 |
1 |
reference |
- |
| methylated (80) |
67 |
12 |
1 |
2.70 (1.31-5.57) |
0.0074 |
|
H. pylori positive (338) |
|
|
|
|
|
| unmethylated (122) |
82 |
37 |
3 |
reference |
- |
| methylated (216) |
179 |
35 |
2 |
2.29 (1.36-3.86) |
0.0018 |
| CDH1 gene methylation |
|
|
|
|
|
| H. pylori negative (189) |
GG |
GA |
AA |
GG vs A carrier; OR (95%C.I.) |
p value |
| unmethylated (129) |
86 |
41 |
2 |
reference |
- |
| methylated (60) |
54 |
6 |
0 |
4.43 (1.76-11.1) |
0.0016 |
| H. pylori positive (338) |
|
|
|
|
|
| unmethylated (152) |
111 |
37 |
4 |
reference |
- |
| methylated (186) | 150 | 35 | 1 | 1.50 (0.900-2.51) | 0.12 |
by logistic regression analysis after adjustment for age and gender.
(): the number of subjects.