Table 2.
Model parameters in the Murray-Salomon basic model
| Symbol | Definition | HIV neg | HIV pos |
|---|---|---|---|
|
ϵUf |
spontaneous cure rate for untreated cases |
0.2 (0.14–0.25)g |
|
|
f |
TB death rate for untreated cases in clinical category i |
|
|
|
|
|
0.12 (0.075–0.20a) |
0.45 (0.3–0.6a) |
|
, |
|
b |
b |
|
gi,k |
proportion of treated cases in clinical category i and treatment category k |
|
|
|
g1,1 |
|
0.5 d |
|
|
g2,1 |
|
0.28 d |
|
|
g3,1 |
|
d |
|
|
gi,2 |
|
gi,2=1−gi,1e |
|
|
f |
cure rate for treated case in treatment category k |
|
|
|
|
|
0.8 |
|
|
|
|
0.5c |
|
|
f |
TB death rate for treated cases in clinical category i and treatment category k |
|
|
|
|
|
0.075c |
0.16c |
|
|
|
0.12c |
0.24c |
|
, |
|
b |
b |
|
rU |
proportion of spontaneously recovered cases entering the slow relapse category |
0.009c |
|
|
|
proportion of recovered cases from treatment category k entering the slow relapse category |
|
|
|
|
|
0.0096c |
|
|
|
|
0.0094c |
|
|
ρFf |
fast relapse rate |
2c |
3 |
|
ρSf |
slow relapse rate |
0.001 (5–15×10−4a) |
|
| γf | rate of HIV infection | 0.075 (0.011–0.95)h |
Model parameters in the Murray-Salomon basic model, Table Two, p.42, in ref. [18], except for K, L, Y and N which are defined in footnote 2 on p.21 of [18]. Where a value is specified only for HIV-negative, the same value is used for HIV-positive.
aFootnote 8, p.24, [18].
bFootnote e, Table A5, p.63, [18].
cTable A5, p.63, [18].
dFootnote †, Table A5, p.63, and Figure A4, p.56 [18].
eFootnote d, Table A5, p.63, [18].
fRate: per person per year.
g[33,34]. Other estimate: 0.05–0.15a.
h[1].