Table 3.
Non-synonymous substitutions* detected in 5 samples with 222 variants (INER047, INER264, INER306, INER307 and INER405)
| Gene | Substitution | Subject: | ||||
|---|---|---|---|---|---|---|
| |
|
INER047 |
INER306 |
INER405 |
INER264 |
INER307 |
| PB1 |
V587G |
X |
X |
X |
|
X |
| |
A652V |
X |
X |
X |
X |
X |
| PB2 |
E191G |
|
X |
|
|
|
| |
Q194H |
X |
X |
X |
X |
X |
| PA |
P224S |
X |
X |
X |
X |
X |
| |
A307G |
X |
|
|
|
|
| |
S395R |
|
X |
|
|
|
| |
P434L |
|
X |
|
|
|
| |
V521I |
|
|
X |
|
|
| |
I573Y |
|
|
X |
|
|
| NP |
S69P |
|
|
|
X |
X |
| |
V100I |
X |
X |
X |
X |
X |
| |
T373I |
|
|
|
X |
|
| NA |
V106I |
X |
X |
X |
X |
X |
| |
N248D |
X |
|
X |
|
|
| |
V304A |
|
|
|
|
X |
| |
T381N |
|
X |
|
X |
X |
| M1 |
I24V |
|
X |
|
|
|
| |
S30R |
|
|
|
X |
|
| |
H222N |
X |
|
|
|
|
| NS2 |
Q20R |
|
X |
X |
X |
X |
| |
L58F |
X |
|
|
|
|
| |
L120F |
|
X |
X |
X |
X |
| NS1 |
V65M |
|
|
X |
|
|
| |
L95P |
|
X |
X |
X |
X |
| |
I123V |
X |
X |
X |
X |
X |
| |
I128T |
X |
|
|
|
|
| |
V180I |
|
X |
X |
|
X |
| |
L181F |
|
|
|
X |
|
| |
P215L |
X |
|
|
|
|
| HA** |
N27D |
|
X |
|
|
|
| |
N48D |
|
X |
X |
|
X |
| |
V169I |
|
X |
|
|
|
| |
G172R |
X |
X |
|
X |
|
| |
S179N |
|
X |
X |
|
X |
| |
W194R |
|
|
|
X |
|
| |
A203T |
|
X |
X |
X |
X |
| |
T214A |
X |
X |
X |
X |
X |
| |
I338V |
X |
X |
X |
X |
X |
| Y528C | X | |||||
* Sequences used for comparison were from Influenza A virus (A/California/04/2009(H1N1)) accession number GQ280797.1.
** HA positions are given without removing the signal peptide.