Figure 5.
Comparison of the Pf-calpain model to the active and inactive forms of the typical calpain. A) Rat calpain 2 without Ca2+ ion (1U5I.pdb). B) Rat calpain 2 complexed with Ca2+ ions (1MDW.pdb). C) The homology model of Pf-calpain subdomain IIa. Catalytic triad residues are displayed in sticks and their residue numbers are marked. Figure is generated by the SYBYL v.8.1.1.